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KMID : 0438420110180010001
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Korean Journal of Bone Metabolism
2011 Volume.18 No. 1 p.1 ~ p.8
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Bone Regeneration from Adipose Stem Cells
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Im Gun-Il
Lee Jai-Sun
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Abstract
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Reconstruction of large bone defect poses a great challenge to an orthopedic surgeon. Recent advancement in stem cell research ushered the treatment of bone defect with tissue-engineered bone into near-possibility. While adipose stem cells (ASCs) are the most available cell sources for tissue regeneration, their low osteogenic potential is adisadvantage. Several strategies have been developed to enhance the osteogenic differentiation of ASCs. In this review, we summarized literatures and our experience on the technology to promote osteogenesis from ASCs.
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KEYWORD
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Adipose tissue, Bone regeneration, Mesenchymal stem cell, Osteogenesis
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